AsianFin – In a groundbreaking study published in the latest issue of Science, Nobel laureate David Baker and his team at the University of Washington have successfully designed a serine hydrolase enzymeentirely from scratch using artificial intelligence (AI). This marks a major milestone in enzyme engineering, demonstrating that AI can now create enzymes with natural catalytic activity and practical application potential. Unlike previous approaches that modified existing enzymes, this research shows that AI can generate complex active sites in enzymes de novo, paving the way for new possibilities in biotechnology, medicine, and industrial applications.